Thank you for passing along this question, Cindy. My reply follows.
I understand the temptation to use an equals sign that does not require a switch to Nemeth Code. However, I must point to the first sentence in #1 under Basic Guidance on When to Switch from the Guidance for Transcription Using the Nemeth Code within UEB Contexts (Approved April 2018). It says (bold added):
Any mathematical expression or chemical formula is transcribed in Nemeth Code. This includes fragmentary expressions, (parts of formulas, incomplete equations, and the like) including isolated signs of operation or comparison.
So, for the print equals signs, we must use the Nemeth Code equals symbol, and we must include within the switch indicators the whole equation (i.e., the codon and, uncontracted, the amino acid).
–Kyle